Anti-Human IgM Heavy Chain Antibody [IM373] (A248962)

Anti-Human IgM Heavy Chain Antibody [IM373]

Mouse monoclonal [IM373] antibody to Human IgM Heavy Chain.

This antibody recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Flow Cytometry, IF, WB, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Recombinant full-length heavy chain of human IgM.

Mouse

Monoclonal

IM373

IgG2b

Unconjugated

Protein A/G chromatography.

200 µg/ml

50-75 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Human IgM Heavy Chain Antibody [IM373] - BSA and Azide free (A252142).