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Anti-IgG3 Antibody

 
Mouse monoclonal (KT133) antibody to IgG3 from Absea Biotechnology (068909H08).
Overview
Name: Anti-IgG3 Antibody
Description: Mouse monoclonal (KT133) antibody to IgG3.
Applications: ELISA, sELISA
Reactivity: Human
Immunogen: Human IgG3.
Host: Mouse
Clonality: Monoclonal
Clone: KT133
Isotype: IgG1
Conjugate: Unconjugated
Purification: IgG is purified through a Protein A column.
Concentration: 1 mg/ml in PBS containing 0.09% sodium azide as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target
Function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Cellular Location: Secreted. Cell membrane.
UniProt: P01860
Gene ID:
Synonyms: DKFZp686H11213 Antibody
FLJ39988 Antibody
FLJ40036 Antibody
FLJ40253 Antibody
FLJ40587 Antibody
FLJ40789 Antibody
FLJ40834 Antibody
HDC Antibody
Heavy chain disease protein Antibody
Ig gamma 3 chain C region Antibody
IGHG3 Antibody
Immunoglobulin heavy constant gamma 3 (G3m marker) Antibody
MGC45809 Antibody
Information: Target information shown above is from the UniProt Consortium.

Images
ELISA - Anti-IgG3 Antibody from Absea Biotechnology (068909H08) - Antibodies.com
ELISA using plates coated with human antibodies with various isotypes.
Sandwich ELISA - Anti-IgG3 Antibody from Absea Biotechnology (068909H08) - Antibodies.com
Sandwich ELISA for purified IgG3 using KT133 coated plate and HRP conjugated KT131.
Sandwich ELISA - Anti-IgG3 Antibody from Absea Biotechnology (068909H08) - Antibodies.com
Sandwich ELISA for normal human serum samples.

Research Areas

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Please Note: Anti-IgG3 Antibody is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | 068909H08
Size Price Quantity
100µg £178
200µg £259
1mg £682

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