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Anti-IgG4 Antibody

 
Mouse monoclonal (KT130) antibody to IgG4 from Absea Biotechnology (068709G12).
Overview
Name: Anti-IgG4 Antibody
Description: Mouse monoclonal (KT130) antibody to IgG4.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Human IgG4.
Host: Mouse
Clonality: Monoclonal
Clone: KT130
Isotype: IgG1
Conjugate: Unconjugated
Purification: IgG is purified through a Protein A column.
Concentration: 1 mg/ml in PBS containing 0.09% sodium azide as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target
Function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Cellular Location: Secreted. Cell membrane.
UniProt: P01861
Synonyms: Ig gamma 4 chain C region Antibody
IGHG4 Antibody
Immunoglobulin heavy constant gamma 4 (G4m marker) Antibody
MGC117419 Antibody
Information: Target information shown above is from the UniProt Consortium.

Images
ELISA - Anti-IgG4 Antibody from Absea Biotechnology (068709G12) - Antibodies.com
ELISA using plates coated with human antibodies with various isotypes.
Western Blot - Anti-IgG4 Antibody from Absea Biotechnology (068709G12) - Antibodies.com
Western blotting using purified IgG4 under reducing conditions.
Sandwich ELISA - Anti-IgG4 Antibody from Absea Biotechnology (068709G12) - Antibodies.com
Sandwich ELISA for purified IgG4.
Sandwich ELISA - Anti-IgG4 Antibody from Absea Biotechnology (068709G12) - Antibodies.com
Sandwich ELISA for normal human serum samples using KT130 coated plate and HRP conjugated KT132.

Research Areas

Related Products
Description: Rabbit monoclonal antibody to IgG4
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Reactivity: Human
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Description: Rabbit Polyclonal Antibody to IGHG4
Application: ELISA, WB, IHC
Host: Rabbit
Isotype: IgG
Immunogen: immunoglobulin heavy constant gamma 4 (G4m marker)

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Please Note: Anti-IgG4 Antibody is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | 068709G12
Size Price Quantity
100µg £178
200µg £259
1mg £682

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