Anti-IL-17B Antibody - BSA and Azide free (A283748)

Anti-IL-17B Antibody - BSA and Azide free

Rabbit polyclonal antibody to IL-17B.

This antibody recognises interleukin-17B (IL-17B) also known as cytokine Zcyto7, IL-20 and neuronal interleukin-17-related factor. IL17B is a member of the IL-17 superfamily of cytokines and is expressed in a wide range of tissues and cell types including human pancreas, small intestine, chondrocytes and neurons. There is limited information about the biological functions of IL17B, but it is known to act as a proinflammatory cytokine inducing TNFa and IL-1ß production in THP-1 cells and stimulating neutrophil infiltration (Bie et al. 2017, Liu et al. 2020). IL-17B has also been reported to induce the migration of CXCR4+ or CXCR5+ germinal center B cells to CXCL12 and CXCL13.

WB, ELISA

ELISA: 0.5 µg/ml - 2.0 µg/ml, WB: 0.1 µg/ml - 0.2 µg/ml

Human

E. coli derived recombinant human interleukin-17B.

Rabbit

Polyclonal

IgG

Unconjugated

Lyophilized

Reconstitute with 0.1 ml of distilled water.

Supplied in Phosphate Buffered Saline.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Human interleukin-17B antibody recognizes interleukin-17B (IL-17B) also known as cytokine Zcyto7, IL-20 and neuronal interleukin-17-related factor. IL17B is a member of the IL-17 superfamily of cytokines and is expressed in a wide range of tissues and cell types including human pancreas, small intestine, chondrocytes and neurons. There is limited information about the biological functions of IL17B, but it is known to act as a proinflammatory cytokine inducing TNFa and IL-1ß production in THP-1 cells and stimulating neutrophil infiltration (Bie et al. 2017, Liu et al. 2020). IL-17B has also been reported to induce the migration of CXCR4+ or CXCR5+ germinal center B cells to CXCL12 and CXCL13 (Bie et al. 2017).

Cytokine like protein Zcyto7, Cytokine Zcyto7, IL 17B, IL 20, IL-20, IL17B, IL17B_HUMAN, IL20, Interleukin 17 beta, Interleukin 17B, Interleukin 20, Interleukin-17B, Interleukin-20, MGC138900, MGC138901, Neuronal interleukin 17 related factor, Neuronal interleukin-17-related factor, NIRF, ZCYTO7