This antibody recognises interleukin-17D (IL-17D), also known as IL-27. IL-17D is a member of the IL-17 family of cytokines. The receptor of 17-D has yet to be identified, although there have been some reports that it is able to interact with the receptor IL-17RA. There is also limited information regarding the biological functions elicited by IL-17D, however it is believed to stimulate the production of other cytokines including IL-6, IL-8 and GM-CSF. IL-17D may also play a role in local immune responses through induction of myeloid growth factors, chemokines, stimulatory local infiltration and proliferation of leukocytes.
E. coli derived recombinant human interleukin-17D.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
1 mg/ml after reconstitution.
Product Form
Lyophilized
Reconstitution
Reconstitute with 0.1 ml of distilled water.
Formulation
Supplied in Phosphate Buffered Saline.
Storage
Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti Human interleukin-17D antibody, recognizes interleukin-17D (IL-17D), also known as IL-27. IL-17D is a member of the IL-17 family of cytokines. The receptor of 17-D has yet to be identified, although there have been some reports that it is able to interact with the receptor IL-17RA. There is also limited information regarding the biological functions elicited by IL-17D, however it is believed to stimulate the production of other cytokines including IL-6, IL-8 and GM-CSF. IL-17D may also play a role in local immune responses through induction of myeloid growth factors, chemokines, stimulatory local infiltration and proliferation of leukocytes (Liu et al. 2020).
Synonyms
IL 17D, IL 22, IL 27, IL-27, IL17D, IL17D_HUMAN, IL27, Interleukin 17D, Interleukin 27, Interleukin-17D, Interleukin-27
