Anti-IL-1RA Antibody (Biotin) - BSA and Azide free (A282267)

Anti-IL-1RA Antibody (Biotin) - BSA and Azide free

Rabbit polyclonal antibody to IL-1RA (Biotin).

This antibody recognises human Interleukin-1 receptor antagonist (IL-1RA), a naturally occurring inflammatory inhibitor protein, produced by monocytes, macrophages, neutrophils, corneal epithelial cells and fibroblasts, which inhibits the activity of IL-1 alpha and IL-1 beta, by competitively blocking binding to cell surface receptors for IL-1.Genetic variations in IL-1RA gene (IL1RN) are associated with susceptibility to microvascular complications of diabetes type 4 (MVCD4), and IL-1RA has therapeutic applications in rheumatoid arthritis, asthma, psoriasis, sepsis, chronic myelogenous leukaemia and inflammatory bowel disease.

WB, ELISA

ELISA: 0.25 - 1 µg/ml, WB: 0.1 - 0.2 µg/ml

Human

Recombinant human IL-1RA.

Rabbit

Polyclonal

IgG

100 µg/ml after reconstitution.

Lyophilized

Reconstitute with 0.5 ml of sterile Phosphate Buffered Saline containing 0.1% Bovine Serum Albumin. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.

Supplied in Phosphate Buffered Saline.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Human interleukin-1 receptor antagonist antibody recognises human Interleukin-1 receptor antagonist (IL-1RA), a naturally occurring inflammatory inhibitor protein, produced by monocytes, macrophages, neutrophils, corneal epithelial cells and fibroblasts, which inhibits the activity of IL-1 alpha and IL-1 beta, by competitively blocking binding to cell surface receptors for IL-1. Genetic variations in IL-1RA gene (IL1RN) are associated with susceptibility to microvascular complications of diabetes type 4 (MVCD4), and IL-1RA has therapeutic applications in rheumatoid arthritis, asthma, psoriasis, sepsis, chronic myelogenous leukaemia and inflammatory bowel disease.

DIRA, F630041P17Rik, ICIL 1RA, ICIL-1RA, ICIL1RA, IL-1ra3, IL-1RN, IL1 inhibitor, IL1F3, IL1RA, IL1RA_HUMAN, IL1RN, IL1RN (IL1F3), Interleukin 1 receptor antagonist, Interleukin-1 receptor antagonist protein, Intracellular IL 1 receptor antagonist type II, Intracellular interleukin 1 receptor antagonist (icIL 1ra), IRAP, MGC10430, MVCD4, Type II interleukin 1 receptor antagonist

This product is for research use only. It is not intended for diagnostic or therapeutic use.