This antibody recognises bovine interleukin-6 (IL-6), a 23.8 kDa cytokine belonging to the IL-6 superfamily.Bovine interleukin-6 is a multifunctional cytokine secreted by a range of cell types, in particular T lymphocytes and macrophages. IL-6 has a range of activities and includes the differentiation of B cells into Ig producing cells, differentiation of lymphocytes and of monocytes. IL-6 functions in both a pro-inflammatory role where it is an important inducer of the acute phase response and also as an anti-inflammatory myokine.
Applications
WB, ELISA
Dilutions
ELISA: 1 µg/ml - 5 µg/ml, WB: 0.1 µg/ml - 2 µg/ml
Reactivity
Bovine
Cross Reactivity
This antibody does not cross react with Cat, Dog, Horse, Human, Mouse, or Pig
Immunogen
Recombinant bovine interleukin-6.
Host
Chicken
Clonality
Polyclonal
Isotype
IgY
Conjugate
Unconjugated
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Storage
Store undiluted at 4°C. Do not freeze! Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Chicken anti Bovine interleukin-6 antibody recognizes bovine interleukin-6 (IL-6), a 23.8 kDa cytokine belonging to the IL-6 superfamily.Bovine interleukin-6 is a multifunctional cytokine secreted by a range of cell types, in particular T lymphocytes and macrophages. IL-6 has a range of activities and includes the differentiation of B cells into Ig producing cells, differentiation of lymphocytes and of monocytes. IL-6 functions in both a pro-inflammatory role where it is an important inducer of the acute phase response and also as an anti-inflammatory myokine (Febbraio & Pedersen 2005).
Recombinant Bovine IL-6 Protein (A320360) detected using Anti-IL-6 Antibody (A283390) as the capture reagent and Anti-IL-6 Antibody (Biotin) (A282283) as the detection reagent followed by Streptavidin:HRP.
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