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Anti-IL1RA Antibody

 
Mouse monoclonal (KT6) antibody to IL1RA from Absea Biotechnology (030104C08).
Overview
Name: Anti-IL1RA Antibody
Description: Mouse monoclonal (KT6) antibody to IL1RA.
Applications: ELISA
Reactivity: Human
Immunogen: Recombinant human IL-1ra.
Host: Mouse
Clonality: Monoclonal
Clone: KT6
Isotype: IgG1
Conjugate: Unconjugated
Purification: IgG is purified through a Protein A column.
Concentration: 1 mg/ml in PBS containing 0.09% sodium azide as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target
Function: Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
Tissue Specificity: The intracellular form of IL1RN is predominantly expressed in epithelial cells.
Involvement in Disease: Microvascular complications of diabetes 4: Pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis.

Interleukin 1 receptor antagonist deficiency: A rare autoinflammatory disease of skin and bone resulting in sterile multifocal osteomyelitis, periostitis, and pustulosis from birth. The term autoinflammatory disease describes a group of disorders characterized by attacks of seemingly unprovoked inflammation without significant levels of autoantibodies and autoreactive T-cells.
Cellular Location: Secreted.
UniProt: P18510
Gene ID: 3557
Synonyms: Antigen CD121a Antibody
CD121 antigen-like family member A Antibody
CD121a Antibody
CD121a antigen Antibody
D2S1473 Antibody
DIRA Antibody
ICIL 1RA Antibody
ICIL-1RA Antibody
ICIL1RA Antibody
IL 1 Antibody
IL 1R 1 Antibody
IL 1R alpha Antibody
IL 1RT1 Antibody
IL-1R-1 Antibody
IL-1R-alpha Antibody
IL-1ra Antibody
IL-1ra3 Antibody
IL-1RN Antibody
IL-1RT-1 Antibody
IL-1RT1 Antibody
IL1 inhibitor Antibody
IL1 Receptor I Antibody
IL1F3 Antibody
IL1R Antibody
IL1R1 Antibody
IL1R1_HUMAN Antibody
IL1RA_HUMAN Antibody
IL1RN Antibody
IL1RN (IL1F3) Antibody
IL1RT1 Antibody
Interleukin 1 receptor alpha type 1 Antibody
Interleukin 1 receptor antagonist Antibody
Interleukin 1 receptor antagonist protein (IRAP) Antibody
Interleukin 1 receptor type I Antibody
Interleukin receptor 1 Antibody
Interleukin-1 receptor alpha Antibody
Interleukin-1 receptor antagonist protein Antibody
Interleukin-1 receptor type 1 Antibody
Interleukin-1 receptor type I Antibody
Intracellular IL 1 receptor antagonist type II Antibody
Intracellular interleukin 1 receptor antagonist (icIL 1ra) Antibody
IRAP Antibody
MGC10430 Antibody
MVCD4 Antibody
p80 Antibody
Type II interleukin 1 receptor antagonist Antibody
Information: Target information shown above is from the UniProt Consortium.

Research Areas

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Please Note: Anti-IL1RA Antibody is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | 030104C08
Size Price Quantity
100µg £178
200µg £259
1mg £682

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