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Anti-IL23 P19 Antibody (Biotin)

 
Rabbit polyclonal antibody to IL23 P19 (Biotin) from FabGennix (IL23P19-BIOTIN).
Overview
Name: Anti-IL23 P19 Antibody (Biotin)
Description: Rabbit polyclonal antibody to IL23 P19 (Biotin)
Applications: ELISA, WB
Dilutions: DB: 1:10,000; ELISA: 1:10,000; Western Blot: 1:250
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide taken within amino acid region 75-105 on IL23P19 protein.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Biotin
Concentration: 0.74-0.90 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Target
Function: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Tissue Specificity: Secreted by activated dendritic and phagocytic cells and keratinocytes. Also expressed by dermal Langerhans cells (at protein level).
Sequence Similarities: Belongs to the IL-6 superfamily.
Cellular Location: Secreted.

Secreted upon association with IL12B.
UniProt: Q9NPF7

Please Note: Anti-IL23 P19 Antibody (Biotin) is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | IL23P19-BIOTIN
Size Price Quantity
100µg £429

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