Anti-IL23 P19 Antibody (FITC)
Rabbit polyclonal antibody to IL23 P19 (FITC) from FabGennix (IL23P19.112-FITC).
|Name:||Anti-IL23 P19 Antibody (FITC)|
|Description:||Rabbit polyclonal antibody to IL23 P19 (FITC)|
|Dilutions:||DB: 1:10,000; ELISA: 1:10,000; Immunocytochemistry: 0; Immunohistochemistry: 0; Immunoprecipitation: 0; Western Blot: 1:250|
|Reactivity:||Human, Mouse, Rat|
|Concentration:||0.74-0.90 µg/µl in antibody stabilization buffer|
|Storage:||-20⁰C for long term storage|
|Function:||Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.|
|Tissue Specificity:||Secreted by activated dendritic and phagocytic cells and keratinocytes. Also expressed by dermal Langerhans cells (at protein level).|
|Sequence Similarities:||Belongs to the IL-6 superfamily.|
Secreted upon association with IL12B.
Please Note: Anti-IL23 P19 Antibody (FITC) is for research use only. It is not intended for diagnostic of therapeutic use.