Anti-iNOS Antibody (A283409)

Anti-iNOS Antibody

Rabbit polyclonal antibody to iNOS.

This antibody recognises inducible nitric oxide synthase also known as iNOS and NOS type II. This enzyme triggers the synthesis of the second messenger molecule, nitric oxide (NO), by immune cells such as macrophages in response to pathogen exposure. Inducible nitric oxide synthase also becomes activated in response to interleukin 1 beta and tumor necrosis factor alpha. In endothelia, the molecule is produced by eNOS (endothelial nitric oxide synthase) where it acts as a vasodilator and platelet inhibitor while in the brain NO is produced by nNOS (neuronal nitric oxide synthase) and functions as a neurotransmitter.

WB, IP

WB: 1:1,000

Mouse, Rat, Bovine

Synthetic peptide corresponding to amino acids 1131-1144 of mouse iNOS.

KKGSALEEPKATRL

Rabbit

Polyclonal

IgG

Unconjugated

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 50% Glycerol and <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti iNOS antibody recognizes inducible nitric oxide synthase also known as iNOS and NOS type II. This enzyme triggers the synthesis of the second messenger molecule, nitric oxide (NO), by immune cells such as macrophages in response to pathogen exposure. Inducible nitric oxide synthase also becomes activated in response to interleukin 1 beta and tumor necrosis factor alpha (Lowenstein and Padalko, 2004). In endothelia, the molecule is produced by eNOS (endothelial nitric oxide synthase) where it acts as a vasodilator and platelet inhibitor while in the brain NO is produced by nNOS (neuronal nitric oxide synthase) and functions as a neurotransmitter.

HEP-NOS, Hepatocyte NOS, HEPNOS, inducible, Inducible nitric oxide synthase, Inducible NO synthase, Inducible NOS, MAC NOS, Macrophage NOS, Nitric oxide synthase, Nitric oxide synthase 2 inducible, Nitric oxide synthase 2 inducible macrophage, nitric oxide synthase 2A (inducible, hepatocytes), Nitric oxide synthase inducible, nitric oxide synthase, macrophage, NOS, NOS 2, Nos II, NOS type II, nos2, NOS2A, NOS2A, Inducible, Hepatocyte, NOS2_HUMAN, Peptidyl-cysteine S-nitrosylase NOS2