Recombinant Anti-Insulin Antibody [rIRDN/8546] (A315191)

$765

Recombinant mouse monoclonal [rIRDN/8546] antibody to Insulin for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Insulin Antibody [rIRDN/8546]
Description
Recombinant mouse monoclonal [rIRDN/8546] antibody to Insulin.
Specificity
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Applications
IHC-P
Positive Control
MIA PaCa-2 cells. Pancreas tissue.
Dilutions
IHC: 0.1-0.2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human Insulin protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
rIRDN/8546
Isotype
IgG2a
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
6 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
IDDM, IDDM1, IDDM2, ILPR, ins, Insulin A chain, Insulin B chain, INS_HUMAN, IRDN, MODY10, Preproinsulin, Proinsulin, Proinsulin precursor
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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