Recombinant Anti-Integrin alpha E Antibody [ITGAE/3904R] (A249061)

Recombinant rabbit monoclonal [ITGAE/3904R] antibody to Integrin alpha E for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Integrin alpha E Antibody [ITGAE/3904R]
Description
Recombinant rabbit monoclonal [ITGAE/3904R] antibody to Integrin alpha E.
Specificity
This antibody recognizes a protein of 150kDa, identified as CD103, which is the alpha-E integrin subunit of the heterodimeric alpha-E beta-7 (aEb7) integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95% of intraepithelial CD8+ cells and on 40% of mucosa-associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. Antibody to CD103 is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL).
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment of human ITGAE protein. The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
ITGAE/3904R
Isotype
IgG
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
150 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Integrin alpha E Antibody [ITGAE/3904R] - BSA and Azide free (A252241).
Synonyms
A530055J10, alpha-E1, alpha-M290, aM290, Antigen CD103, CD 103, CD103, CD103 antigen, HML 1 antigen, HML-1 antigen, HML1 antigen, Human mucosal lymphocyte antigen 1, Human mucosal lymphocyte antigen 1, alpha subunit, Huminae, Integrin alpha E heavy chain, Integrin alpha E light chain, Integrin alpha E, epithelial-associated, Integrin alpha E1, Integrin alpha IEL, Integrin alpha M290, Integrin alpha-E heavy chain, Integrin alpha-IEL, Integrin, alpha E, Integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide), ITAE_HUMAN, Itgae, MGC141996, MGC183601, Mucosal lymphocyte 1 antigen, Mucosal lymphocyte antigen 1
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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