Anti-Interferon alpha 1 Antibody [2-48] (A248917)

Anti-Interferon alpha 1 Antibody [2-48]

Mouse monoclonal [2-48] antibody to Interferon alpha 1.

This antibody is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

Flow Cytometry, WB, IHC, IF

Flow Cytometry: 1-2 µg/million cells, WB: 1-2 µg/ml, IF: 1-2 µg/ml

Human

Recombinant human IFN alpha 1.

Mouse

Monoclonal

2-48

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

16-27 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Interferon alpha 1 Antibody [2-48] - BSA and Azide free (A252097).

IFL, IFN, IFN alpha, IFN alpha 1/13, IFN alpha 1b, IFN alphaD, IFN-alpha-1/13, IFNA1, IFNA13, IFNA1_HUMAN, IFNA@, Interferon alpha, Interferon alpha-1/13, Interferon alpha-D, Interferon alpha1, Interferon, alpha 13, LeIF D