Anti-IRGM Antibody (A283257)

$450

Rabbit polyclonal antibody to IRGM for WB, IHC-P and IF.

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-IRGM Antibody
Description
Rabbit polyclonal antibody to IRGM.
Specificity
This antibody recognises human Immunity-related GTPase family M protein (IRGM), also known as LRG47.IRGM is a putative GTPase required for clearance of bacterial and protozoan infections. It funtions in the innate immune response, most likely through regulation of autophagy.IRGM may also function in the regulation of proinflammatory cytokine production and in macrophage adhesion and motility.
Applications
WB, IHC-P, IF
Dilutions
IF: 20 µg/ml, IHC-P: 5 µg/ml, WB: 1 - 2 µg/ml
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide corresponding to 14 amino acids near the centre of human IRGM.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate

Unconjugated

Concentration
1 mg/ml
Molecular Weight
Approximately 32 kDa in human brain cell lysate.
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti IRGM (Internal Region) antibody recognizes human Immunity-related GTPase family M protein (IRGM), also known as LRG47.IRGM is a putative GTPase required for clearance of bacterial and protozoan infections. It funtions in the innate immune response, most likely through regulation of autophagy.IRGM may also function in the regulation of proinflammatory cytokine production and in macrophage adhesion and motility.
Synonyms
IFI1, Iigp3, Iipg3, Immunity related GTPase family M protein 1, Immunity related GTPase family, M, Immunity-related GTPase family M protein, Immunity-related GTPase family M protein 1, Interferon inducible protein 1, Interferon-inducible protein 1, IRGM1, IRGM_HUMAN, LPS-stimulated RAW 264.7 macrophage protein 47 homolog, LRG 47, LRG-47, LRG-47-like protein, LRG47, MGC149263, MGC149264
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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