Anti-AHSG Anticorpo [AHSG/3748] (A277583)

Name: Anti-AHSG Antibody [AHSG/3748]
Brand: Antibodies.com
SKU: A277583
Price: 525.0 USD
Availability: InStock

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$525

Anticorpo monoclonale [AHSG/3748] di topo contro AHSG per IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Carrier Free and Preservative Free

Consegna

Spese di spedizione

$40

Tempi di consegna

4-6 Giorni lavorativi

Contattaci

Telefono

+1 (314) 370-6046

E-mail

orders@antibodies.com

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Garanzia di qualità al 100%

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Tag dei prodotti:

Anticorpo Monospecifico

Descrizione Prodotto

Nome

Anti-AHSG Antibody [AHSG/3748]

Descrizione

Mouse monoclonal [AHSG/3748] antibody to AHSG.

Specificità

Fetuin (also designated Î±2-z-globulin or Î±2-HS-glycoprotein) is a secreted plasma protein that is expressed in hepatocytes, monocyte/macrophages and in bone and is downregulated during injury and inflammation. Fetuin preferentially binds to and carries calcium and barium ions in the blood, where it is thought to mediate serum calcium homeostasis and mineralization, and to potentially participate in the transport of bioactive molecules. Additionally, fetuin has been shown to function as an acute phase anti-inflammatory mediator that is critical to regulating the innate immune response following tissue injury. During inflammation, circulating fetuin levels substantially decrease as fetuin becomes associated with the membranes of macrophages. This membrane associated form of fetuin acts as an opsonic participant by potentiating the entry of cationic small molecules into the activated macro-phage, which in turn facilitates macrophage-deactivating mechanisms. Biologically active fetuin is derived from a precursor protein that is cleaved at the aminoterminus to generate two chains held together by a single disulfide bond.

Applicazioni

IHC-P

Diluizioni consigliate

IHC-P: 1-2 µg/ml

Reattività

Human

Immunogeno

Recombinant fragment corresponding to human AHSG protein. The exact sequence is proprietary.

Specie ospite

Mouse

Clonalità

Monoclonal

Clona ID

AHSG/3748

Isotipo

IgG1

Catene leggere

kappa

Coniugare

Unconjugated

Purificazione

Protein A/G chromatography.

Concentrazione

200 µg/ml

Peso molecolare

59 kDa

Forma del prodotto

Liquid

Formulazione

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Conservazione

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Note generali

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-AHSG Antibody [AHSG/3748] - BSA and Azide free (A278171).

Sinonimi

59 kDa bone sialic acid-containing protein, A2HS, Aa2-066, AHS, Ahsg alpha-2-HS-glycoprotein, Alpha 2 HS Glycoprotein, Alpha 2 Z globulin, Alpha-2-HS-glycoprotein, Alpha-2-HS-glycoprotein chain B, Alpha-2-Z-globulin, Asialofetuin, Ba alpha 2 glycoprotein, Ba-alpha-2-glycoprotein, BSP, Countertrypin, Fetua, FETUA_HUMAN, Fetuin , mouse, homolog of, Fetuin A, Fetuin-A, Glycoprotein PP63, HSGA, pp63

Controlli isotipo

Secondari adatti

Dichiarazione di non responsabilità

Questo prodotto è solo per uso di ricerca. Non è inteso per uso diagnostico o terapeutico.

Immagini (3)

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Figure 1: Immunohistochemistry - Anti-AHSG Antibody [AHSG/3748] (A277583)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human placenta tissue using Anti-AHSG Antibody [AHSG/3748] at 2µg/ml. Inset: PBS instead of the primary antibody. Secondary antibody negative control.

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Figure 2: SDS-PAGE - Anti-AHSG Antibody [AHSG/3748] (A277583)

SDS-PAGE analysis of Anti-AHSG Antibody [AHSG/3748] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

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Figure 3: Anti-AHSG Antibody [AHSG/3748] (A277583)

Analysis of protein array containing more than 19,000 full-length human proteins using Anti-AHSG Antibody [AHSG/3748]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt^TM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt^TM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.