AHSG è un gene codificato dal simbolo AHSG. Altri nomi includono: Alpha-2-HS-glycoprotein; Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-A; FETUA. AHSG ha una massa di 39.34kDa, una lunghezza di amminoacidi di 367, ed è implicato in Alopecia-mental retardation syndrome 1.
Offriamo 8 anticorpi contro AHSG, allevati nel Coniglio e Topo, che sono adatti per WB, IHC e ICC/IF con campioni derivati da Umano.
Informazioni su geni e proteine
Riepilogo UniProt
Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.
Sommario di Entrez
The protein encoded by this gene is a negatively-charged serum glycoprotein that is synthesized by hepatocytes. The encoded protein consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several processes, including endocytosis, brain development, and the formation of bone tissue. Defects in this gene are a cause of susceptibility to leanness.
Specificità del tessuto
Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.
Coinvolgimento nella malattia
Alopecia-mental retardation syndrome 1: A rare autosomal recessive form of alopecia. APMR1 patients show loss of hair on the scalp, absence of eyebrows, eyelashes, axillary and pubic hair, and mild to severe mental retardation.
Somiglianze di sequenza
Belongs to the fetuin family.
Modifica post-translazionale
Phosphorylated by FAM20C in the extracellular medium.
Posizione cellulare
Secreted.
