This antibody recognises the human CD89 cell surface antigen, a 50-75 kDa cell surface glycoprotein that is also known as the IgA receptor (Fc alpha R).CD89 is expressed by peripheral blood monocytes and neutrophils.MIP8a blocks binding of IgA to the Fc alpha R, and also inhibits neutrophil phagocytosis of IgA complexes.
Applicazioni
IP, Flow Cytometry, ELISA
Diluizioni consigliate
Flow Cytometry: 1:50 - 1:100, Use 10µl of the suggested working dilution to label 106 cells or 100µl whole blood
Reattività
Human
Immunogeno
Recombinant soluble human Fc alpha R.
Specie ospite
Mouse
Clonalità
Monoclonal
Clona ID
MIP8a
Isotipo
IgG1
Coniugare
Unconjugated
Concentrazione
1 mg/ml
Forma del prodotto
Liquid
Formulazione
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Conservazione
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Note generali
Mouse anti Human CD89 antibody, clone MIP8a recognizes the human CD89 cell surface antigen, a 50-75 kDa cell surface glycoprotein that is also known as the IgA receptor (Fc alpha R).CD89 is expressed by peripheral blood monocytes and neutrophils.MIP8a blocks binding of IgA to the Fc alpha R, and also inhibits neutrophil phagocytosis of IgA complexes.
Sinonimi
Fc alpha receptor, Fc fragment of IgA, receptor for, FCAR, FCAR_HUMAN, IgA Fc receptor, Immunoglobulin alpha Fc receptor
