Anti-G-CSF Anticorpo (A283011)

Anti-G-CSF Antibody - BSA and Azide free

Rabbit polyclonal antibody to G-CSF.

This antibody recognises human G-CSF (Granulocyte colony-stimulating factor), a 19.6kDa haematopoietic growth factor and member of the CSF family of hormone-like glycoproteins, which stimulates the development of bone marrow progenitor cells and in particular those committed to neutrophil lineage.The ability of G-CSF to stimulate the proliferation/differentiation and function of neutrophil granulocyte progenitor cells and survival of mature neutrophils, has resulted in G-CSF becoming an important factor in patient treatment following allogeneic (bone marrow/stem cell) transplantation and chemotherapy.To yield one-half maximal inhibition [ND50] of the biological activity of hG-CSF (0.5 ng/ml), a concentration of 0.04-0.06 ug/ml of this antibody is required.

WB, ELISA, IHC-P, Functional Assays

ELISA: 0.5 µg/ml - 2 µg/ml, Functional Assays: 0.04 - 0.06 µg/ml, IHC-P: 0.25 µg/ml, WB: 0.1 - 0.2 µg/ml

Human

Recombinant human G-CSF.

Rabbit

Polyclonal

IgG

Unconjugated

1 mg/ml after reconstitution.

Reconstitute with 0.1 ml of distilled water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide.

Supplied in Phosphate Buffered Saline.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Human G-CSF antibody recognizes human G-CSF (Granulocyte colony-stimulating factor), a 19.6kDa haematopoietic growth factor and member of the CSF family of hormone-like glycoproteins, which stimulates the development of bone marrow progenitor cells and in particular those committed to neutrophil lineage.The ability of G-CSF to stimulate the proliferation/differentiation and function of neutrophil granulocyte progenitor cells and survival of mature neutrophils, has resulted in G-CSF becoming an important factor in patient treatment following allogeneic (bone marrow/stem cell) transplantation and chemotherapy.To yield one-half maximal inhibition [ND50] of the biological activity of hG-CSF (0.5 ng/ml), a concentration of 0.04-0.06 ug/ml of this antibody is required.

C17orf33, Colony stimulating factor 3, Colony stimulating factor 3 (granulocyte), CSF 3, CSF beta , CSF3, CSF3OS, CSF3_HUMAN, Csfg, Filgrastim, GCSA, GCSF, Granulocyte colony stimulating fact, Granulocyte colony stimulating factor, Granulocyte colony-stimulating factor, Lenograstim , Macrophage granulocyte inducer 2, MGC45931, MGI 2, MGI IG, OTTMUSP00000006785, Pluripoietin, RP23-395E10.4