Anti-G-CSF Anticorpo [SPM468] (A248276)

Anti-G-CSF Antibody [SPM468]

Mouse monoclonal [SPM468] antibody to G-CSF.

This antibody recognizes granulocyte-colony stimulating factor (G-CSF) in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell types. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.G-CSF is a pleiotropic cytokine that influences differentiation, proliferation and activation of the neutrophilic granulocyte lineage. The human G-CSF cDNA encodes a 207 amino acid precursor containing a 29 amino acid signal peptide that is proteolytically cleaved to form a 178 amino acid residue mature protein. Two G-CSFs share 73% sequence identity at the amino acid level.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human, Macaque Monkey

Nuclei from pokeweed mitogen stimulated human peripheral blood lymphocytes.

Mouse

Monoclonal

SPM468

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

19 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-G-CSF Antibody [SPM468] - BSA and Azide free (A251458).

C17orf33, Colony stimulating factor 3, Colony stimulating factor 3 (granulocyte), CSF 3, CSF beta , CSF3, CSF3OS, CSF3_HUMAN, Csfg, Filgrastim, GCSA, GCSF, Granulocyte colony stimulating fact, Granulocyte colony stimulating factor, Granulocyte colony-stimulating factor, Lenograstim , Macrophage granulocyte inducer 2, MGC45931, MGI 2, MGI IG, OTTMUSP00000006785, Pluripoietin, RP23-395E10.4