CD32 è un gene codificato dal simbolo FCGR2A. Altri nomi includono: Low affinity immunoglobulin gamma Fc region receptor II-a; IgG Fc receptor II-a; CDw32; Fc-gamma RII-a; Fc-gamma-RIIa; FCGR2A; FCG2; FCGR2A1; IGFR2. CD32 ha una massa di 35kDa e una lunghezza di amminoacidi di 317.
Offriamo 29 anticorpi contro CD32, allevati nel Coniglio, Topo, Capra e Ratto, che sono adatti per WB, IHC, ELISA, ICC/IF, Citometria a Flusso e IP con campioni derivati da Umano, Topo, Ratto, Bovino, Maiale, Pecora e Cane.
Informazioni su geni e proteine
Riepilogo UniProt
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Sommario di Entrez
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
Specificità del tessuto
Found on monocytes, neutrophils and eosinophil platelets.
Modifica post-translazionale
Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.
Posizione cellulare
Cell membrane.
