Recombinant rabbit monoclonal [VWF/1859R] antibody to Von Willebrand Factor.
Specificità
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
Applicazioni
WB, IHC-P
Diluizioni consigliate
WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reattività
Human
Immunogeno
Recombinant fragment, around amino acids 1815-1939, of human vWF protein. The exact sequence is proprietary.
Specie ospite
Rabbit
Clonalità
Monoclonal
Clona ID
VWF/1859R
Isotipo
IgG
Coniugare
Unconjugated
Purificazione
Protein A chromatography.
Concentrazione
200 µg/ml
Peso molecolare
250 kDa
Forma del prodotto
Liquid
Formulazione
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Conservazione
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Coagulation factor VIII , Coagulation factor VIII VWF, F8VWF, Factor VIII related antigen, von Willebrand antigen 2, von Willebrand antigen II, Von Willebrand disease, VWD, vWF, VWF_HUMAN
Figure 2: Western Blot - Anti-Von Willebrand Factor Antibody [VWF/1859R] (A250329)
Western blot analysis of (A) recombinant Von Willebrand Factor protein and (B) human lung lysate using Anti-Von Willebrand Factor Antibody [VWF/1859R].
SDS-PAGE analysis of Anti-Von Willebrand Factor Antibody [VWF/1859R] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.
Prodotti alternativi a Anti-Von Willebrand Factor Anticorpo [VWF/1859R] (A250329)