Anti-Junctional Adhesion Molecule 1 Antibody (FITC)
Rabbit polyclonal antibody to Junctional Adhesion Molecule 1 (FITC) from FabGennix (JAMA-FITC).
|Name:||Anti-Junctional Adhesion Molecule 1 Antibody (FITC)|
|Description:||Rabbit polyclonal antibody to Junctional Adhesion Molecule 1 (FITC)|
|Dilutions:||DB: 1:10,000; ELISA: 1:10,000; Western Blot: 1:500|
|Reactivity:||Bovine, Monkey, Mouse, Panda, Rat|
|Immunogen:||Synthetic peptide corresponding to human JamaA protein.|
|Concentration:||0.52-0.63 µg/µl in antibody stabilization buffer|
|Storage:||-20⁰C for long term storage|
|Function:||Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840).|
|Tissue Specificity:||Expressed in endothelium, epithelium and leukocytes (at protein level).|
|Sequence Similarities:||Belongs to the immunoglobulin superfamily.|
|Cellular Location:||Cell junction > Tight junction. Cell membrane.
Localized at tight junctions of both epithelial and endothelial cells.
|Synonyms:||CD 321 Antibody
CD321 antigen Antibody
F11 receptor Antibody
JAM 1 Antibody
JAM A Antibody
Junction adhesion molecule 1 Antibody
Junction adhesion molecule, mouse, homolog of Antibody
Junctional adhesion molecule A Antibody
PAM 1 Antibody
Platelet adhesion molecule Antibody
Platelet adhesion molecule 1 Antibody
Platelet F11 receptor Antibody
|Information:||Target information shown above is from the UniProt Consortium.|
Please Note: Anti-Junctional Adhesion Molecule 1 Antibody (FITC) is for research use only. It is not intended for diagnostic of therapeutic use.