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Anti-Junctional Adhesion Molecule 1 Antibody (FITC)

 
Rabbit polyclonal antibody to Junctional Adhesion Molecule 1 (FITC) from FabGennix (JAMA-FITC).
Overview
Name: Anti-Junctional Adhesion Molecule 1 Antibody (FITC)
Description: Rabbit polyclonal antibody to Junctional Adhesion Molecule 1 (FITC)
Applications: ELISA, WB
Dilutions: DB: 1:10,000; ELISA: 1:10,000; Western Blot: 1:500
Reactivity: Bovine, Monkey, Mouse, Panda, Rat
Immunogen: Synthetic peptide corresponding to human JamaA protein.
Host: Rabbit
Clonality: Polyclonal
Conjugate: FITC
Concentration: 0.52-0.63 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Target
Function: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840).
Tissue Specificity: Expressed in endothelium, epithelium and leukocytes (at protein level).
Sequence Similarities: Belongs to the immunoglobulin superfamily.
Post-Translational Modification: N-glycosylated.
Cellular Location: Cell junction > Tight junction. Cell membrane.

Localized at tight junctions of both epithelial and endothelial cells.
UniProt: Q9Y624
Synonyms: CD 321 Antibody
CD321 Antibody
CD321 antigen Antibody
ESTM33 Antibody
F11 receptor Antibody
F11R Antibody
JAM Antibody
JAM 1 Antibody
JAM A Antibody
JAM-1 Antibody
JAM-A Antibody
JAM1 Antibody
JAM1_HUMAN Antibody
JAMA Antibody
JCAM Antibody
Jcam1 Antibody
Junction adhesion molecule 1 Antibody
Junction adhesion molecule, mouse, homolog of Antibody
Junctional adhesion molecule A Antibody
KAT Antibody
Ly106 Antibody
PAM 1 Antibody
PAM-1 Antibody
PAM1 Antibody
Platelet adhesion molecule Antibody
Platelet adhesion molecule 1 Antibody
Platelet F11 receptor Antibody
PRO301 Antibody
UNQ264 Antibody
Information: Target information shown above is from the UniProt Consortium.


Please Note: Anti-Junctional Adhesion Molecule 1 Antibody (FITC) is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | JAMA-FITC
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100µg £429

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