Anti-Kappa Light Chain Antibody [HP6053] - BSA and Azide free (A252160)

Anti-Kappa Light Chain Antibody [HP6053] - BSA and Azide free

Mouse monoclonal [HP6053] antibody to Kappa Light Chain.

This antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Flow Cytometry, WB, IHC-P

Flow Cytometry: 0.5-2 µg/million cells, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Purified human Ig kappa chain.

Mouse

Monoclonal

HP6053

IgG1

kappa

Protein A/G chromatography.

1 mg/ml

~22.5 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Kappa Light Chain Antibody [HP6053] (A248980).

HCAK 1, HCAK1, Ig kappa chain C region, IGKC, IGKCD, Immunoglobulin InV, Immunoglobulin kappa constant, Immunoglobulin kappa constant region, Immunoglobulin kappa light chain, Immunoglobulin kappa light chain constant region, Immunoglobulin KM, Kappa 1 immunoglobulin light chain, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809