Anti-Kappa Light Chain Antibody [HP6053 + L1C1] - BSA and Azide free (A252161)

Mouse monoclonal [HP6053 + L1C1] antibody to Kappa Light Chain for WB and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Kappa Light Chain Antibody [HP6053 + L1C1] - BSA and Azide free
Description
Mouse monoclonal [HP6053 + L1C1] antibody to Kappa Light Chain.
Specificity
This antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Applications
WB, IHC-P
Dilutions
WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Clone HP6053: Purified human Ig kappa chain. Clone L1C1: Human B-lymphoma cells.
Host
Mouse
Clonality
Oligoclonal
Clone ID
HP6053 + L1C1
Isotype
IgG1, kappa + IgG1, kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
~22.5 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes

Please note, this product is an oligoclonal antibody; it is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies not only have the specificity and batch-to-batch consistency of a monoclonal antibody, but they also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen.

This oligoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Kappa Light Chain Antibody [HP6053 + L1C1] (A248981).

Synonyms
HCAK 1, HCAK1, Ig kappa chain C region, IGKC, IGKCD, Immunoglobulin InV, Immunoglobulin kappa constant, Immunoglobulin kappa constant region, Immunoglobulin kappa light chain, Immunoglobulin kappa light chain constant region, Immunoglobulin KM, Kappa 1 immunoglobulin light chain, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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