Anti-Ku70 Antibody (A283495)

$420

Rabbit polyclonal antibody to Ku70 for WB and IHC-P.

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Ku70 Antibody
Description
Rabbit polyclonal antibody to Ku70.
Specificity
This antibody recognises human Ku70, also known as XRCC6, G22P1 or X-ray repair cross-complementing protein 6.Ku70 is involved in repair of double stranded DNA breaks via the non-homologous end joining (NHEJ) pathway. Ku70 forms a heterodimer with Ku80 (Ku70/Ku80), which binds to the ends of broken DNA where it recruits proteins for end-processing and ligation.
Applications
WB, IHC-P
Dilutions
IHC-P: 1:50 - 1:200, WB: 1:500 - 1:2,000
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human Ku70.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate

Unconjugated

Concentration
Lot Specific
Molecular Weight
Approximately 70 kDa in cell and tissue lysates under reducing conditions
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Storage
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti Ku70 antibody recognizes human Ku70, also known as XRCC6, G22P1 or X-ray repair cross-complementing protein 6.Ku70 is involved in repair of double stranded DNA breaks via the non-homologous end joining (NHEJ) pathway. Ku70 forms a heterodimer with Ku80 (Ku70/Ku80), which binds to the ends of broken DNA where it recruits proteins for end-processing and ligation.
Synonyms
5''-deoxyribose-5-phosphate lyase Ku70, 5''-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP dependent DNA helicase 2 subunit 1, ATP dependent DNA helicase II 70 kDa subunit, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, G22P1, Ku 70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, Ku p70, Ku70 DNA binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa, Kup70, Lupus Ku autoantigen protein p70, ML8, Thyroid autoantigen, Thyroid autoantigen 70kD (Ku antigen), Thyroid lupus autoantigen, Thyroid lupus autoantigen p70, Thyroid-lupus autoantigen, TLAA, X ray repair complementing defective repair in Chinese hamster cells 6, X-ray repair complementing defective repair in Chinese hamster cells 6, X-ray repair cross-complementing protein 6, XRCC 6, Xrcc6, XRCC6_HUMAN
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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