Recombinant Anti-L-PLUNC Antibody [LPLUNC1/7059R] (A278095)

Anti-L-PLUNC Antibody [LPLUNC1/7059R]

Recombinant rabbit monoclonal [LPLUNC1/7059R] antibody to L-PLUNC.

The upper respiratory tract is the main place of entry for pathogens to invade the body, and early recognition of bacterial products in this region is crucial for host defense. Palate lung nasal epithelial clone PLUNC (or LUNX) is an airway specific secretory protein that is expressed in epithelial tissues and submucosal glands of the oral cavity and upper respiratory tract of humans, mice, rats and cows. PLUNC binds to lipopolysaccharide (LPS) in nasal lavage fluid (NLF) which points to its role in the inflammatory response of the upper airways after exposure to irritants. Decreased levels of PLUNC occur in the NLF of smokers and people who have been exposed to reactive epoxy chemicals, indicating that long-term exposure to airway irritants impairs the production of PLUNC in the upper respiratory tract. Abnormal expression of PLUNC may influence susceptibility to nasopharyngeal carcinoma in the Chinese population.

ELISA, WB, IHC-P

WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Recombinant full-length human L-PLUNC protein.

Rabbit

Monoclonal

LPLUNC1/7059R

IgG

Unconjugated

Protein A/G chromatography.

200 µg/ml

25 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-L-PLUNC Antibody [LPLUNC1/7059R] - BSA and Azide free (A278683).