Anti-LIM kinase 2 Antibody (Biotin)
Rabbit polyclonal antibody to LIM kinase 2 (Biotin) from FabGennix (LIMK2-BIOTIN).
|Name:||Anti-LIM kinase 2 Antibody (Biotin)|
|Description:||Rabbit polyclonal antibody to LIM kinase 2 (Biotin)|
|Dilutions:||DB: 1:10,000; ELISA: 1:10,000; Western Blot: 1:500|
|Reactivity:||Human, Mouse, Rat|
|Immunogen:||Synthetic peptide taken within amino acid region 570-638 on human LIMK2 protein.|
|Concentration:||0.55-0.75 µg/µl in antibody stabilization buffer|
|Storage:||-20⁰C for long term storage|
|Function:||Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.|
|Tissue Specificity:||Overexpressed in several esophageal squamous cell carcinomas (ESCs).|
|Sequence Similarities:||Belongs to the JHDM3 histone demethylase family.|
|Synonyms:||LIM domain kinase 2 Antibody
LIMK 2 Antibody
|Information:||Target information shown above is from the UniProt Consortium.|
Please Note: Anti-LIM kinase 2 Antibody (Biotin) is for research use only. It is not intended for diagnostic of therapeutic use.