Anti-Luteinizing Hormone Antibody [LHCGR/1417] (A249232)

Anti-Luteinizing Hormone Antibody [LHCGR/1417]

Mouse monoclonal [LHCGR/1417] antibody to Luteinizing Hormone.

This antibody recognizes a protein of 78-85kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.

ELISA, Flow Cytometry, WB

Flow Cytometry: 1-2 µg/million cells, WB: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 70-410, of human LHCGR protein. The exact sequence is proprietary.

Mouse

Monoclonal

LHCGR/1417

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

78-85 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Luteinizing Hormone Antibody [LHCGR/1417] - BSA and Azide free (A252412).

CGB4, HH23, hLHB, Interstitial cell stimulating hormone beta chain, Leutropin, LH B, LH-B, LHB, LSH B, LSH beta, LSH-B, LSH-beta, LSHB_HUMAN, Luteinizing hormone beta, Luteinizing hormone beta subunit, Luteinizing hormone subunit beta, Lutropin beta chain, Lutropin subunit beta