Anti-Metapneumovirus Antibody [HMPV24] (A280638)

Anti-Metapneumovirus Antibody [HMPV24]

Mouse monoclonal [HMPV24] antibody to Metapneumovirus.

This antibody recognises human metapneumovirus (hMPV), a member of the Paramyxoviridae RNA virus family. Metapneumovirus was discovered in 2001 and is distributed worldwide. Infection in the upper respiratory tract is associated with mild illness, while lower respiratory tract infection can cause fever, cough, pneumonia, bronchiolitis and wheezing. Severe lower respiratory tract infection is most common in the very young, the very old and the immunosuppressed. Metapneumovirus is a common cause of respiratory infection.Phylogenetic analysis has shown two major genotypes, A and B, each containing two sub-divisions, suggesting that four distinct lineages circulate in the population with different lineages predominating in different years.recognises the fusion protein of all sub-types (A1, A2, B1 and B2) of hMPV and may be used in conjunction with clones HMPV57, HMPV123 and HMPV33 to detect all strains of hMPV. Mouse anti Metapneumovirus antibody, clone HMPV24 does not cross-react with cell cultures infected with hRSV, influenzaviruses A and B, adenovirus, parainfluenza viruses 1, 2, 3 and 4b, mumps virus, measles virus, varicella-zoster virus, herpes simplex virus types 1 and 2, human cytomegalovirus, human herpesvirus type 6, ECHOvirus 19, Coxsachievirus B4, poliovirus types 1-3, HHV6 or uninfected HeLa, MA104, 3MK, LLC-MK, HEp2, MRC-5 and HSB-2 cells. It also does not react with sputum bacteria.

IF: 1:40 - 1:80

Viral

Sub-type A hMPV virus isolate NCL03-4/145.

Mouse

Monoclonal

HMPV24

IgG2a

Unconjugated

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Metapneumovirus antibody, clone HMPV24 recognizes human metapneumovirus (hMPV), a member of the Paramyxoviridae RNA virus family. Metapneumovirus was discovered in 2001 and is distributed worldwide. Infection in the upper respiratory tract is associated with mild illness, while lower respiratory tract infection can cause fever, cough, pneumonia, bronchiolitis and wheezing. Severe lower respiratory tract infection is most common in the very young, the very old and the immunosuppressed. Metapneumovirus is a common cause of respiratory infection.Phylogenetic analysis has shown two major genotypes, A and B, each containing two sub-divisions, suggesting that four distinct lineages circulate in the population with different lineages predominating in different years.Mouse anti Metapneumovirus antibody, clone HMPV24 recognizes the fusion protein of all sub-types (A1, A2, B1 and B2) of hMPV and may be used in conjunction with clones HMPV57, HMPV123 and HMPV33 to detect all strains of hMPV. Mouse anti Metapneumovirus antibody, clone HMPV24 does not cross-react with cell cultures infected with hRSV, influenzaviruses A and B, adenovirus, parainfluenza viruses 1, 2, 3 and 4b, mumps virus, measles virus, varicella-zoster virus, herpes simplex virus types 1 and 2, human cytomegalovirus, human herpesvirus type 6, ECHOvirus 19, Coxsachievirus B4, poliovirus types 1-3, HHV6 or uninfected HeLa, MA104, 3MK, LLC-MK, HEp2, MRC-5 and HSB-2 cells. It also does not react with sputum bacteria.

hMPV