Anti-MHC Class I Monomorphic Antibody [73-2] (A279505)

Anti-MHC Class I Monomorphic Antibody [73-2]

Mouse monoclonal [73-2] antibody to MHC Class I Monomorphic.

This antibody recognises the lapine homologue of the human major histocompatibility complex (MHC) class Ib, a protein expressed at varying levels on the cell surface of the majority of nucleated rabbit cells.MHC genes are found in all vertebrate species. The nomenclature varies for different species, often collectively named as leukocyte antigens and prefixed by the species or species group, e.g. human leukocyte antigen (HLA), bovine leukocyte antigen (BoLA) etc. Rabbit major histocompatibility complex molecules are generally referred to as MHC, however some sources have referenced them as Rabbit leukocyte antigens (RLA). MHC molecules comprise a vital component of adaptive immunity, MHC class I molecules are glycoproteins that function in the presentation of antigen fragments from antigen processing cells to cytotoxic T cells. Mouse anti Rabbit MHC class I monomorphic, clone 73-2 is specific for the rabbit MHC class Ib and provides a useful flow cytometry marker of rabbit nucleated cells.

Flow Cytometry: 1:50 - 1:200, Use 10µl of the suggested working dilution to label 10⁶ cells or 100µl whole blood

Rabbit

Rabbit T cells.

Mouse

Monoclonal

73-2

IgG1

Protein A affinity chromatography of tissue culture supernatant.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Rabbit MHC class I monomorphic, clone 73-2, recognizes the lapine homologue of the human major histocompatibility complex (MHC) class Ib, a protein expressed at varying levels on the cell surface of the majority of nucleated rabbit cells.MHC genes are found in all vertebrate species. The nomenclature varies for different species, often collectively named as leukocyte antigens and prefixed by the species or species group, e.g. human leukocyte antigen (HLA), bovine leukocyte antigen (BoLA) etc. Rabbit major histocompatibility complex molecules are generally referred to as MHC, however some sources have referenced them as Rabbit leukocyte antigens (RLA). MHC molecules comprise a vital component of adaptive immunity, MHC class I molecules are glycoproteins that function in the presentation of antigen fragments from antigen processing cells to cytotoxic T cells.Mouse anti Rabbit MHC class I monomorphic, clone 73-2 is specific for the rabbit MHC class Ib and provides a useful flow cytometry marker of rabbit nucleated cells.