Anti-MHC Class II Antibody [M5/114] - BSA and Azide free (A85589)

Anti-MHC Class II Antibody [M5/114] - BSA and Azide free

Rat monoclonal [M5/114] antibody to MHC Class II.

This antibody recognizes a shared extracellular determinant on I-Ab, I-Ad, I-Aq, and I-Ed, I-Ek alloantigens, but it does not react with I-Af, I-Ak, I-As. This antibody can inhibit I-A-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not H-2f, H-2k, H-2s haplotypes.

Flow Cytometry, IP, WB, IHC-P, IHC-Fr, Functional Studies

FUNC: Blocking of T cell proliferative responses, Flow Cytometry: 2 µg/ml, IHC: 5-10 µg/ml.

Mouse

Activated C57BL/6 mouse spleen cells.

Rat

Monoclonal

M5/114

Protein G chromatography.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline, pH 7.4, without Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.