ISO 9001:2015 Certified
Live Customer Support
4.5/5 on Trustpilot
100% Quality Guarantee

Anti-MHC Class II Monomorphic Antibody [IL-A21] (A280728)

This product is discontinued

Anti-MHC Class II Monomorphic Antibody [IL-A21] (A280728) has been discontinued and is no longer available.

View all available products.

Name
Anti-MHC Class II Monomorphic Antibody [IL-A21]
Description
Mouse monoclonal [IL-A21] antibody to MHC Class II Monomorphic.
Specificity
This antibody recognises a monomorphic epitope within the bovine MHC II cell surface antigen. Clone IL-A21 is reported to react with an epitope which is common to both BoLA DR and DQ. Expression of MHC II molecules have been demonstrated on bovine B cells, activated T cells, alveolar macrophages, monocytes and mammary and bronchial epithelial cells. Clone IL-A21 is reported to inhibit T cell proliferation following FMDV infection.
Applications
IP, Flow Cytometry
Dilutions
Use 10µl of the suggested working dilution to label 1x106 cells in 100µl.
Reactivity
Bovine
Host
Mouse
Clonality
Monoclonal
Clone ID
IL-A21
Isotype
IgG2a
Conjugate

Unconjugated

Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Bovine MHC Class II Monomorphic antibody, clone IL-A21 recognizes a monomorphic epitope within the bovine MHC II cell surface antigen. Clone IL-A21 is reported to react with an epitope which is common to both BoLA DR and DQ (Howard et al.1997).Expression of MHC II molecules have been demonstrated on bovine B cells, activated T cells, alveolar macrophages, monocytes and mammary and bronchial epithelial cells. Clone IL-A21 is reported to inhibit T cell proliferation following FMDV infection (Collen et al. 1991).
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.