Anti-MHC Class II Monomorphic Antibody [IL-A21] (FITC) (A280726)

Anti-MHC Class II Monomorphic Antibody [IL-A21] (FITC)

Mouse monoclonal [IL-A21] antibody to MHC Class II Monomorphic (FITC).

This antibody recognises a monomorphic epitope within the bovine MHC II cell surface antigen. Clone IL-A21 is reported to react with an epitope which is common to both BoLA DR and DQ. Expression of MHC II molecules have been demonstrated on bovine B cells, activated T cells, alveolar macrophages, monocytes and mammary and bronchial epithelial cells. Clone IL-A21 is reported to inhibit T cell proliferation following FMDV infection.

Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Bovine

Mouse

Monoclonal

IL-A21

Protein G affinity chromatography of tissue culture supernatant.

100 µg/ml

Liquid

Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Mouse anti Bovine MHC Class II Monomorphic antibody, clone IL-A21 recognizes a monomorphic epitope within the bovine MHC II cell surface antigen. Clone IL-A21 is reported to react with an epitope which is common to both BoLA DR and DQ (Howard et al.1997).Expression of MHC II molecules have been demonstrated on bovine B cells, activated T cells, alveolar macrophages, monocytes and mammary and bronchial epithelial cells. Clone IL-A21 is reported to inhibit T cell proliferation following FMDV infection (Collen et al. 1991).

This product is for research use only. It is not intended for diagnostic or therapeutic use.