This antibody recognizes a common extracellular epitope on MICA and MICB glycoproteins, transmembrane ligands of NKG2D, and is able to block NKG2D-mediated activation of NK cells and cytotoxic T cells.
Applications
Flow Cytometry
Dilutions
Flow Cytometry: 1-6 µg/ml
Reactivity
Human
Immunogen
Transfected C1R cells expressing MICA.
Host
Mouse
Clonality
Monoclonal
Clone ID
6D4
Isotype
IgG2a
Conjugate
Alexa Fluor® 647
Excitation: 650nm, Emission: 665nm
Purification
This antibody is conjugated with Alexa Fluor® 647 under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Concentration
0.1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 15mM Sodium Azide.
Storage
Store in the dark at 2-8°C. Do not freeze!
Synonyms
MHC class I chain-related protein A, MHC class I chain-related protein B, MHC class I polypeptide related sequence A, MHC class I polypeptide related sequence B, MHC class I polypeptide-related sequence A, MIC-A, micA, MICA_HUMAN, MICB
