Anti-MORF4 Antibody (A283164)

Anti-MORF4 Antibody

Rabbit polyclonal antibody to MORF4.

This antibody recognises human Mortality Factor 4 (MORF4), known also as SEN1 and cellular senescence-related protein 1.MORF4 is a nuclear localized protein possessing transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that are believed to allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription co-repressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.

WB, IHC-P

IHC-P: 5 µg/ml, WB: 1 µg/ml

Human, Mouse, Rat

A peptide corresponding to 18 amino acids near the N-terminus of human MORF4.

Rabbit

Polyclonal

IgG

Approximately 33 kDa in K562 cell lysates.

Liquid

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti MORF4 antibody recognizes human Mortality Factor 4 (MORF4), known also as SEN1 and cellular senescence-related protein 1.MORF4 is a nuclear localized protein possessing transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that are believed to allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription co-repressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.