Anti-NACC1 Antibody [PCRP-NACC1-1A8] (A248213)

Mouse monoclonal [PCRP-NACC1-1A8] antibody to NACC1 for Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-NACC1 Antibody [PCRP-NACC1-1A8]
Description
Mouse monoclonal [PCRP-NACC1-1A8] antibody to NACC1.
Specificity
The BTB (broad-complex, tramtrack and bric a brac) domain, also known as the POZ (poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B), also known as NACC1 (nucleus accumbens associated 1), BEND8 or NAC1, is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homo-oligomer that interacts with HDAC3 and HDAC4, BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas, suggesting a role in tumor development and metastasis.
Applications
Flow Cytometry
Dilutions
Flow Cytometry: 1-2 µg/million cells
Reactivity
Human
Immunogen
Recombinant full-length human NACC1 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-NACC1-1A8
Isotype
IgG2a
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
57 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-NACC1 Antibody [PCRP-NACC1-1A8] - BSA and Azide free (A251396).
Synonyms
BEND8, BTB Domain Containing 14B, BTB/POZ domain-containing protein 14B, btbd14b, FLJ37383, NAC-1, Nac1, NACC1_HUMAN, Nucleus accumbens-associated protein 1
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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