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Anti-NAV1 Antibody

 
Rat monoclonal (KT127) antibody to NAV1 from Absea Biotechnology (161801F01).
Overview
Name: Anti-NAV1 Antibody
Description: Rat monoclonal (KT127) antibody to NAV1.
Applications: WB, IF
Reactivity: Human
Immunogen: Recombinant NAV1 (aa742 - aa1008).
Amino Acid Start: 177
Amino Acid End: 420
Host: Rat
Clonality: Monoclonal
Clone: KT127
Isotype: IgG2a
Conjugate: Unconjugated
Purification: Antibody is purified from culture supernatant using a protein G column.
Concentration: 1 mg/ml in PBS containing 0.09% sodium azide as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target
Function: May be involved in neuronal migration.
Tissue Specificity: Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta.
Sequence Similarities: Belongs to the Nav/unc-53 family.
Cellular Location: Cytoplasm > Cytoskeleton.

Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones (By similarity).
UniProt: Q8NEY1
Gene ID: 89796
Synonyms: DKFZp781D0314 Antibody
FLJ12560 Antibody
FLJ14203 Antibody
KIAA1151 Antibody
MGC14961 Antibody
mNav1 Antibody
mouse Nav1 Antibody
Nav 1 Antibody
Neuron navigator 1 Antibody
POMFIL 3 Antibody
POMFIL3 Antibody
Pore membrane and/or filament interacting like protein 3 Antibody
Protein Steerin 1 Antibody
Protein Steerin1 Antibody
Steerin 1 Antibody
Steerin1 Antibody
unc-53 homolog 1 Antibody
UNC53H1 Antibody
Information: Target information shown above is from the UniProt Consortium.

Specific Citations

van Haren J et al. Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension. Curr. Biol. 24(15): 1778-1785 (2014)

van Haren J et al. Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension. Curr. Biol. 24(15): 1778-1785 (2014)



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Description: Rabbit Polyclonal Antibody to neuron navigator 1
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Please Note: Anti-NAV1 Antibody is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | 161801F01
Size Price Quantity
100µg £186
200µg £273
1mg £730

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