+44 (0)1223 298875

Anti-NCOA1 Antibody

Rabbit polyclonal antibody to NCOA1 from ABclonal (A0765).
Name: Anti-NCOA1 Antibody
Description: Rabbit polyclonal antibody to NCOA1.
Applications: WB
Dilutions: WB: 1:500 - 1:1000.
Reactivity: Human
Immunogen: A synthetic peptide of human NCOA1.
Protein Length: 1441
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response. Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3.
Tissue Specificity: Widely expressed.
Sequence Similarities: Belongs to the SRC/p160 nuclear receptor coactivator family.
Post-Translational Modification: Sumoylated; sumoylation increases its interaction with PGR and prolongs its retention in the nucleus. It does not prevent its ubiquitination and does not exert a clear effect on the stability of the protein.
Cellular Location: Nucleus.
UniProt: Q15788
Gene ID: 8648
Synonyms: bHLHe74 Antibody
Class E basic helix-loop-helix protein 74 Antibody
F SRC 1 Antibody
Hin 2 protein Antibody
Hin2 protein Antibody
KAT13A / SRC1 Antibody
MGC129719 Antibody
MGC129720 Antibody
mNRC 1 Antibody
NCoA 1 Antibody
NCoA-1 Antibody
NCOA1_HUMAN Antibody
Nuclear receptor coactivator 1 Antibody
Nuclear receptor coactivator protein 1 Antibody
NY REN 52 antigen Antibody
Protein Hin 2 Antibody
Protein Hin-2 Antibody
Protein Hin2 Antibody
Renal carcinoma antigen NY REN 52 Antibody
Renal carcinoma antigen NY-REN-52 Antibody
RIP 160 Antibody
RIP160 Antibody
SRC 1 Antibody
SRC-1 Antibody
Steroid receptor coactivator 1 Antibody
Information: Target information shown above is from the UniProt Consortium.
Western blot analysis of extracts of various cell lines, using NCOA1 antibody.
Please Note: All batches are extensively validated and are guaranteed to work as specified, however, QC data is not necessarily from the current lot on sale.
Description: Rabbit polyclonal antibody to NCOA1
Application: WB, IF
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human NCOA1.

£234

Description: Rabbit polyclonal antibody to NCOA1.
Application: WB, IHC, IF
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

£148 – £372

Description: Rabbit polyclonal antibody to NCoA-1
Application: WB, IHC, IF
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant full length Human NCOA1.

£220 – £366

Description: Rabbit Polycolonal antibody to SRC-1 (Phospho-Thr1179)
Application: WB
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: A synthesized peptide derived from human SRC-1 (Phospho-Thr1179)

£180 – £234

Please Note: Anti-NCOA1 Antibody is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | A0765
Size Price Quantity
100µl £243
200µl £372

or
Request a quotation
Contact Us Directly
  • call icon + 44 (0)1223 298 875
  • + 44 (0)1223 281 447
  • email icon info@antibodies.com
Product Quality
  • guarantee icon
  • We promise guaranteed product quality
  • and expert customer service.
Lead Time: Currently 4-6 Days
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe