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Anti-Neurochondrin Antibody (Biotin)

Rabbit polyclonal antibody to Neurochondrin (Biotin) from FabGennix (NORB-BIOTIN).
Name: Anti-Neurochondrin Antibody (Biotin)
Description: Rabbit polyclonal antibody to Neurochondrin (Biotin)
Applications: ELISA, IF, IHC, IP, WB
Dilutions: DB: 1;10,000; DB: 1;10,000; ELISA: 1;10,000; Western Blot: 1:500; Western Blot: 1:500; Western Blot: 1:500
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide corresponding to unique amino acid sequence on rat NORBIN protein.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Biotin
Concentration: 0.64-0.72 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Function: Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.
Tissue Specificity: Expressed in brain and in peripheral nervous system (at protein level). Weakly expressed in neurites.
Sequence Similarities: Belongs to the neurochondrin family.
Cellular Location: Cytoplasm > Cytosol. Cell projection > Dendrite.

Localizes to somatic regions of neurons.
UniProt: O35095
Gene ID:
Synonyms: AU042419 Antibody
KIAA0607 Antibody
M-Sema F-associating protein of 75 kDa Antibody
MGC93259 Antibody
MMS10-AE Antibody
Ms10ae Antibody
NCDN Antibody
NCDN-1 Antibody
NCDN-2 Antibody
Neurochondrin 1 Antibody
Norbin Antibody
OTTHUMP00000065369 Antibody
OTTHUMP00000065370 Antibody
OTTHUMP00000065371 Antibody
Sfap75 Antibody
Information: Target information shown above is from the UniProt Consortium.

Please Note: Anti-Neurochondrin Antibody (Biotin) is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | NORB-BIOTIN
Size Price Quantity
100µg £429

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