Anti-NeuroD2 Antibody [PCRP-NEUROD2-1G1] - BSA and Azide free (A278311)

Mouse monoclonal [PCRP-NEUROD2-1G1] antibody to NeuroD2 for ELISA, IP, Flow Cytometry and IF.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-NeuroD2 Antibody [PCRP-NEUROD2-1G1] - BSA and Azide free
Description
Mouse monoclonal [PCRP-NEUROD2-1G1] antibody to NeuroD2.
Specificity
Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (β2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix(bHLH) transcription factorsthat function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.
Applications
ELISA, IP, Flow Cytometry, IF
Dilutions
IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human NeuroD2 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-NEUROD2-1G1
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
41 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-NeuroD2 Antibody [PCRP-NEUROD2-1G1] (A277723).
Synonyms
bHLHa1, class A basic helix loop helix protein 1, Class A basic helix-loop-helix protein 1, NDF2_HUMAN, NDR2, NDRF, neuroD related factor, NeuroD-related factor, neurogenic basic helix loop helix protein, neurogenic differentiation 2, Neurogenic differentiation factor 2, neuronal differentiation 2
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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