Anti-Neurofilament Heavy Polypeptide Antibody [NF421] (A249487)

Mouse monoclonal [NF421] antibody to Neurofilament Heavy Polypeptide for Flow Cytometry, IF, WB and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Neurofilament Heavy Polypeptide Antibody [NF421]
Description
Mouse monoclonal [NF421] antibody to Neurofilament Heavy Polypeptide.
Specificity
This antibody reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Applications
Flow Cytometry, IF, WB, IHC-P
Dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 0.25-0.5 µg/ml
Reactivity
Human, Mouse, Rat, Porcine, Chicken
Immunogen
Recombinant full-length human NEFH protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
NF421
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
200 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Neurofilament Heavy Polypeptide Antibody [NF421] - BSA and Azide free (A252667).
Synonyms
200 kDa neurofilament protein, CMT2CC, Nefh, Neurofilament heavy polypeptide 200kDa, Neurofilament triplet H protein, NF H, NF-H, NFH, NFH_HUMAN
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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