Anti-NME2 Antibody [NME2/4160] (A315396)

$765

Mouse monoclonal [NME2/4160] antibody to NME2 for WB and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-NME2 Antibody [NME2/4160]
Description
Mouse monoclonal [NME2/4160] antibody to NME2.
Specificity
The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.
Applications
WB, IHC-P
Positive Control
MCF-7, A549, HeLa or Jurkat cells. Ubiquitously expressed in all tissues.
Dilutions
WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human NME2 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
NME2/4160
Isotype
IgG2
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
17 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
C myc purine binding transcription factor PUF, C myc transcription factor, C-myc purine-binding transcription factor PUF, epididymis secretory sperm binding protein Li 155an, HEL-S-155an, Histidine protein kinase NDKB, MGC111212, MGC2212, NDK B, NDKB, NDKB_HUMAN, NDP kinase B, NDPK B, NDPKB, NM23 H2, nm23-H2, NM23B, NME/NM23 nucleoside diphosphate kinase 2, Non metastatic cells 2, protein (NM23B) expressed in, non-metastatic cells 2, protein (NM23) expressed in, Nucleoside diphosphate kinase B, Nucleotide diphosphate kinase B, PUF
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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