Anti-NOC4L Antibody [PCRP-NOC4L-1E3] (A250368)

Mouse monoclonal [PCRP-NOC4L-1E3] antibody to NOC4L for Flow Cytometry and IF.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-NOC4L Antibody [PCRP-NOC4L-1E3]
Description
Mouse monoclonal [PCRP-NOC4L-1E3] antibody to NOC4L.
Specificity
Treg activation is critical for maintaining self-tolerance, but the translational control of this process is still poorly understood. Zhu et al. report a conserved ribosome biogenesis factor, Noc4L, that regulates mRNAs related to Treg and Tconv activation but does not affect global protein translation. Noc4L regulates translation of mRNAs related to Treg activation. Noc4L plays critical roles in activation of Tregs and Tconvs. Noc4L-mediated ribosome biogenesis is critical in controlling the activation of Tregs and maintaining immune tolerance. [Zhu et al., 2019, Cell Reports 27, 1205 1220.]
Applications
Flow Cytometry, IF
Dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human NOC4L protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-NOC4L-1E3
Isotype
IgG1
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
58.4 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-NOC4L Antibody [PCRP-NOC4L-1E3] - BSA and Azide free (A253548).
Synonyms
AI326906, MGC28606, MGC3162, NET49, NOC4, NOC4 like protein, NOC4 protein homolog, NOC4-like protein, NOC4L_HUMAN, Nucleolar complex associated 4 homolog (S. cerevisiae), Nucleolar complex protein 4 homolog, Nucleolar complex-associated protein 4 like protein, Nucleolar complex-associated protein 4-like protein, OTTMUSP00000032269, RGD1310661
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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