Recombinant Anti-pan Cytokeratin Antibody [KRTH/1576R + KRTL/1577R] (A251012)

Recombinant rabbit monoclonal [KRTH/1576R + KRTL/1577R] antibody to pan Cytokeratin for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-pan Cytokeratin Antibody [KRTH/1576R + KRTL/1577R]
Description
Recombinant rabbit monoclonal [KRTH/1576R + KRTL/1577R] antibody to pan Cytokeratin.
Specificity
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It may be useful to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has high sensitivity in the recognition of epithelial cells and carcinomas.
Applications
IHC-P
Dilutions
IHC-P: 0.25-0.5 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human KRT76 and KRT77 proteins.
Host
Rabbit
Clonality
Monoclonal
Clone ID
KRTH/1576R + KRTL/1577R
Isotype
IgG
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
40-67 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-pan Cytokeratin Antibody [KRTH/1576R + KRTL/1577R] - BSA and Azide free (A254191).
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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