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Anti-PDPN Antibody

Rabbit polyclonal antibody to PDPN from ABclonal (A0956).
Name: Anti-PDPN Antibody
Description: Rabbit polyclonal antibody to PDPN.
Applications: WB, IHC
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
Reactivity: Human
Immunogen: Recombinant protein of human PDPN.
Protein Length: 162
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels.
Tissue Specificity: Highly expressed in placenta, lung, skeletal muscle and brain. Weakly expressed in brain, kidney and liver. In placenta, expressed on the apical plasma membrane of endothelium. In lung, expressed in alveolar epithelium. Up-regulated in colorectal tumors and expressed in 25% of early oral squamous cell carcinomas.
Sequence Similarities: Belongs to the podoplanin family.
Post-Translational Modification: Extensively O-glycosylated. Contains sialic acid residues. O-glycosylation is necessary for platelet aggregation activity.
Cellular Location: Membrane. Cell projection > Filopodium membrane. Cell projection > Lamellipodium membrane. Cell projection > Microvillus membrane. Cell projection > Ruffle membrane.

Localized to actin-rich microvilli and plasma membrane projections such as filopodia, lamellipodia and ruffles.
UniProt: Q86YL7
Gene ID: 10630
Synonyms: Aggrus Antibody
Glycoprotein 36 Antibody
Glycoprotein 36 KD Antibody
gp 36 Antibody
GP 38 Antibody
GP 40 Antibody
gp36 Antibody
GP38 Antibody
GP40 Antibody
HT1A 1 Antibody
HT1A1 Antibody
hT1alpha 1 Antibody
hT1alpha 2 Antibody
hT1alpha1 Antibody
hT1alpha2 Antibody
Lung type I cell membrane associated glycoprotein Antibody
Lung type I cell membrane associated glycoprotein isoform a Antibody
Lung type I cell membrane associated glycoprotein T1A 2 Antibody
OTS 8 Antibody
OTS8 Antibody
OTTHUMP00000009640 Antibody
OTTHUMP00000044504 Antibody
PA2.26 Antibody
PA2.26 antigen Antibody
PDPN_HUMAN Antibody
Podoplanin Antibody
Podoplanin / gp36 Antibody
PSEC0003 Antibody
PSEC0025 Antibody
T1 alpha Antibody
T1 ALPHA GENE Antibody
T1-alpha Antibody
T1A Antibody
T1A 2 Antibody
TI1A Antibody
TIA 2 Antibody
TIA2 Antibody
Information: Target information shown above is from the UniProt Consortium.
Western Blot - Anti-PDPN Antibody from ABclonal (A0956) - Antibodies.com
Western blot analysis of extracts of 293T cell line, using PDPN antibody.
Please Note: All batches are extensively validated and are guaranteed to work as specified, however, QC data is not necessarily from the current lot on sale.
Description: Rabbit polyclonal antibody to PDPN
Application: WB, IHC
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of human podoplanin

£234

Total Citations (2)
Description: Goat polyclonal antibody to PDPN.
Application: ELISA, WB
Host: Goat
Isotype: IgG
Reactivity: Human

£205

Description: Rabbit polyclonal antibody to Podoplanin
Application: ELISA, IHC, IP, WB
Host: Rabbit
Reactivity: Human, Monkey, Mouse
Immunogen: Synthetic peptide taken within amino acid region 30-100 on human Podoplanin protein.

£372

Description: Rabbit polyclonal antibody to PDPN.
Application: WB
Host: Rabbit
Isotype: IgG
Reactivity: Human

£148 – £372

Please Note: Anti-PDPN Antibody is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | A0956
Size Price Quantity
50µl £243
100µl £372
200µl £565

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Lead Time: Currently 4-6 Days
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  • £35 to Europe