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Anti-Phospholipase A2 IIA Antibody

 
Rabbit polyclonal antibody to Phospholipase A2 IIA from FabGennix (PLA2G2A-101AP).
Overview
Name: Anti-Phospholipase A2 IIA Antibody
Description: Rabbit polyclonal antibody to Phospholipase A2 IIA
Applications: ELISA, IMM, WB
Dilutions: DB: 1:10,000; ELISA: 1:10,000; Immunoprecipitation: 1:200; Western Blot: 1:500
Reactivity: Human
Immunogen: Synthetic peptide taken within amino acid region 50-150 on human Phospholipase A2 membrane associated protein.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Concentration: 0.68 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Target
Function: Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536).
Sequence Similarities: Belongs to the phospholipase A2 family.
Cellular Location: Cell membrane. Secreted.
UniProt: P14555
Gene ID:
Synonyms: EC 3.1.1.4 Antibody
GIIC sPLA2 Antibody
Group IIA phospholipase A2 Antibody
membrane associated Antibody
MOM1 Antibody
Non pancreatic secretory phospholipase A2 Antibody
Non-pancreatic secretory phospholipase A2 Antibody
NPS PLA2 Antibody
NPS-PLA2 Antibody
NPSPLA2 Antibody
PA2GA_HUMAN Antibody
Phosphatidylcholine 2 acylhydrolase Antibody
Phosphatidylcholine 2-acylhydrolase 2A Antibody
Phospholipase A2 Antibody
Phospholipase A2 group IIA (platelets synovial fluid) Antibody
Phospholipase A2 membrane associated precursor Antibody
PLA2 Antibody
PLA2B Antibody
PLA2G2A Antibody
PLA2L Antibody
PLA2S Antibody
PLAS1 Antibody
RASF A Antibody
RASFA Antibody
sPLA2 Antibody
Information: Target information shown above is from the UniProt Consortium.


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Please Note: Anti-Phospholipase A2 IIA Antibody is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | PLA2G2A-101AP
Size Price Quantity
100µg £372

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