Anti-Placental Alkaline Phosphatase Antibody [rALP/870] (A277617)

Anti-Placental Alkaline Phosphatase Antibody [rALP/870]

Mouse monoclonal [rALP/870] antibody to Placental Alkaline Phosphatase.

This antibody recognizes a 70kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP This antibody recognizes germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.

WB, IHC-P

WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Recombinant full-length human ALPP protein.

Mouse

Monoclonal

rALP/870

IgG1

kappa

Unconjugated

Protein A/G chromatography.

70 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Placental Alkaline Phosphatase Antibody [rALP/870] - BSA and Azide free (A278205).

Akp2, Alkaline Phosphatase, Alkaline phosphatase intestinal, Alkaline phosphatase intestinal precursor, Alkaline phosphatase liver/bone/kidney, Alkaline phosphatase liver/bone/kidney isozyme, Alkaline phosphatase placental, Alkaline phosphatase placental like, Alkaline phosphatase placental like 2, Alkaline phosphatase placental type, Alkaline phosphatase tissue nonspecific isozyme, Alkaline phosphatase, germ cell, Alkaline phosphatase, liver, Alkaline phosphatase, testicular and thymus, Alkaline phosphatase, tissue-nonspecific, Alkaline phosphomonoesterase, ALP, ALP 1, ALP I, ALP L, ALP P, ALPG, Alpi, ALPL, ALPP, ALPPL, ALPPL2, AP TNAP, FLJ40094, GCAP, Germ cell alkaline phosphatase, Glycerophosphatase, HOPS, IAP, Intestinal alkaline phosphatase, Intestinal-type alkaline phosphatase, Kasahara isozyme, Liver/bone/kidney type alkaline phosphatase, Nagao isozyme, OTTHUMP00000164357, Placental like alkaline phosphatase, PLAP, PLAP 1, PLAP like, PPBI_HUMAN, Regan isozyme, Testicular and thymus alkaline phosphatase, Tissue non specific alkaline phosphatase, Tissue nonspecific ALP, TNAP, TNSALP