Recombinant Anti-RCAS1 Antibody [rEBAG9/7264] (A315544)

$765

Recombinant mouse monoclonal [rEBAG9/7264] antibody to RCAS1 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-RCAS1 Antibody [rEBAG9/7264]
Description
Recombinant mouse monoclonal [rEBAG9/7264] antibody to RCAS1.
Specificity
EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients.
Applications
IHC-P
Positive Control
MCF-7, Jurkat or HEK-293 cell lysates. Human skeletal muscle tissue.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human EBAG9 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
rEBAG9/7264
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
32 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
BAG9, Cancer associated surface antigen, Cancer associated surface antigen RCAS1, Cancer-associated surface antigen RCAS1, EB9, EBAG 9, EBAG9, Estrogen receptor binding fragment associated gene 9 protein, Estrogen receptor binding site associated antigen 9, estrogen receptor binding site associated, antigen, 9, Estrogen receptor-binding fragment-associated gene 9 protein, PDAF, RCAS 1, RCAS1_HUMAN, Receptor binding cancer antigen expressed on SiSo cells, Receptor-binding cancer antigen expressed on SiSo cells
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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