Anti-Semaphorin 4D Antibody [133-1C6] (A248144)

Anti-Semaphorin 4D Antibody [133-1C6]

Mouse monoclonal [133-1C6] antibody to Semaphorin 4D.

This antibody recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI; Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

Flow Cytometry, IF

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Human, Baboon

This antibody does not react with Horse.

PHA stimulated human peripheral blood lymphocytes.

Mouse

Monoclonal

133-1C6

IgM

Unconjugated

200 µg/ml

50 kDa (monomer)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Semaphorin 4D Antibody [133-1C6] - BSA and Azide free (A254298).

A8, BB 18, BB18, CD 100, CD100, CD100 antigen, Coll 4, COLL4, Collapsin 4, Collapsin4, GR3, Leukocyte activation antigen CD100, M sema G, MSEMA, SEM4D_HUMAN, Sema 4d, Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4D, Sema H, SEMA J, Sema4d, Semacl 2, Semacl2, SemaH, SEMAJ, Semaphorin C like 2, Semaphorin H, Semaphorin J, Semaphorin-4D, Semaphorin4D, SemaphorinJ, Semcl 2, Semcl2